ea0029p500 | Diabetes | ICEECE2012
Ameri P.
, Bruzzone S.
, Briatore L.
, Mannino E.
, Basile G.
, Ponta M.
, Grozio A.
, Magnone M.
, Guida L.
, Scarfi S.
, Salis A.
, Damonte G.
, Sturla L.
, Nencioni A.
, Fenoglio D.
, Fiory F.
, Miele C.
, Beguinot F.
, Maggi D.
, Cordera R.
, Murialdo G.
, De Flora A.
, Zocchi E.
Abscissic acid (ABA) is a hormone best known for its role in plants. We previously showed that it is released by pancreatic beta-cells upon glucose stimulation, and autocrinally enhances insulin secretion.Here we additionally report that ABA promotes glucose uptake by rat L6 myoblasts and murine 3T3-L1 cells differentiated to adipocytes, at least partly by inducing GLUT-4 translocation to the plasma membrane.To determine whether AB...